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Broncos Overcome Eagles in Thrilling Finish

Denver's quarterback connected with a short scoring throw and the running back added another rushing score in the final period as the Denver Broncos erased a 14-point deficit to hand the Philadelphia Eagles their first loss of the season. The Broncos deflected the Eagles quarterback's final pass on the game's concluding play to send the Super Bowl champions to just their second loss in their previous 22 outings. Denver (three wins and two losses) got fortunate in their rally when the Philadelphia had a late fourth-down conversion nullified on a formation infraction whistled against running back Saquon Barkley.

Texans Dominate Depleted Ravens in Record Win

CJ Stroud passed for 244 passing yards and four touchdowns, and the Texans (two wins and three losses) strolled to a decisive victory over an injury-ravaged Ravens squad, equaling both the most lopsided road win in Texans' history and the most lopsided home loss in Ravens' history. Baltimore (1-4) were without two-time MVP quarterback Lamar Jackson, and that was not their sole issue. Key defenders Kyle Hamilton, Roquan Smith and Marlon Humphrey all were absent, and the Baltimore already were depleted on that side of the ball because of a neck problem that ended Nnamdi Madubuike's season. Baltimore were also without Pro Bowl blocker Ricard and offensive lineman Stanley.

Las Vegas Raiders 6–40 Indianapolis Colts

Jonathan Taylor ran for three rushing scores and a two-point conversion, and the quarterback passed for two touchdown passes as the Indianapolis Colts overwhelmed the Raiders. The 34-point margin was Indy's biggest since 2013. The quarterback finished 20 of 29 for 212 yards and moved to four wins and one loss as a starter this season, surpassing his total wins over the past two seasons with the New York Giants. Taylor rushed 17 attempts for 66 yards and grabbed three receptions for 20 yards. Indianapolis converted a blocked punt, two interceptions and a turnover on downs into TDs. Las Vegas dropped to 4-1.

Cowboys Soar Past Jets in High-Scoring Game

Dak Prescott passed for four touchdown passes, guiding the Dallas Cowboys to an easy victory over the Jets. Dallas put points on the board on two long marches in the second quarter, despite missing key linemen on the blocking unit. Javonte Williams ran for 135 yards and a score and also hauled in a receiving touchdown. The Cowboys, now two wins, two losses, and a tie, rebounded from a high-scoring draw against the Packers last Sunday. The Jets are still without a victory at zero wins and five losses in Aaron Glenn's first season as head coach.

Minnesota Vikings 21–17 Cleveland Browns

Vikings receiver Addison grabbed a short scoring reception from the quarterback with 25 seconds remaining to secure Minnesota a win over the Cleveland Browns at the UK venue. The 10-play, 80-yard drive gave the Vikings (3-2) a crucial victory on their historic international road trip, which started with a 24-21 loss to the Steelers in Ireland last Sunday. It also spoiled the rookie's debut as starter, as the Browns rookie positioned his squad (1-4) in contention by throwing two touchdown passes. Fellow rookie Quinshon Judkins gained 110 rushing yards on 23 attempts. The quarterback shook off a shoulder injury that briefly forced him out and directed two scoring drives in the second half.

Panthers Stage Epic Comeback Against Dolphins

Carolina's quarterback threw for two touchdowns and Rico Dowdle rushed for 206 yards and a touchdown as the Panthers came back against the Dolphins in their home stadium. Young's short pass to rookie tight end Mitchell Evans with under two minutes to play gave the Panthers (two wins and three losses) the decisive advantage as they equaled the biggest rally to win a game in team history by overcoming a large deficit. The QB had a horrific first quarter, but he finished 19-for-30 passing for 198 yards with one pick. Dowdle, replacing injured Chuba Hubbard, did his work on the ground on 23 carries, coming up four yards shy of the team's all-time rushing mark. Miami's quarterback completed 27 of 36 for 256 yards with three touchdowns and receiver Waddle accumulated 110 receiving yards on six receptions and added a score, but the Miami (one win and four losses) dropped to 0-3 in away contests.

Saints Secure First Win Under New Coach

New Orleans' quarterback threw a long score to receiver Shaheed, safety Jordan Howden scooped up a loose ball 86 yards for a touchdown, and the Saints defeated the error-prone New York Giants for the Saints' first victory under rookie coach Kellen Moore. Rattler earned his first victory in 11 career starts, throwing for 225 yards without a turnover. Giants rookie QB Jaxson Dart, who won his first career start last Sunday, threw for 202 yards and two scores, but also committed errors three times. New York gave up possession on five separate plays in all, none more costly than when the defender forced a fumble from ball carrier Skattebo, resulting in the safety's touchdown. Each squad are one win and four losses.